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Leucocytoclastic...vasculitis...associated...with...acquired...reactive...perforating...collagenosis:...a...diagnostic...mimicryAcquired..reactive..perforating..collagenosisThe..perforating..dermatoses..differ..mainly..in..histopathologic..findings;..differential..diagnosis..based..only..on..clinical..morphology..seems..to..be..nearly..impossibleReactive..perforating..collagenosis..associated..with..diabetes..mellitusThus,....the....presented....case....is....unique....concerning....two....characteristics:....(1)....the....occurrence....of....an....acquired....reactive....perforating....collagenosis....lacking....classical....associations,....such....as....diabetes....mellitus....or....renal....disorders....and....(2)....the....coincidence....of....a....perforating....disease....with....LV.

Acquired...reactive...perforating...collagenosisToggle..Sidebar..Find..Previous..Next..Page:..Presentation..Mode..Open..Print..Download..Current..View..Tools..Zoom..Out..Zoom..In..Automatic..Zoom..Actual..Size..Fit..Page..Full..Width..50%..75%..100%..125%..150%..200%..300%..400%..Rapini..RP,..Herbert..AA,..Drucker..CRThe....patient....had....a....history....of....type....2....diabetes....for....15....yearsHowever,....in....the....following....weeks,....the....patient....developed....a....distinct,....palpable....purpura....with....progression....to....ulcerated....and....necrotic....petechial....skin....lesions....involving....the....lower....extremities....(FigOral....mucosa,....vaginal....mucosa,....and....cutaneous....appendages....were....normalMoreover,..an..expert..on..endocrinology..was..invited..for..a..consultation..to..control..the..blood..glucose[PMC..free..article]..[PubMed]5[PubMed]17doi:...10.1097/MD.0000000000004305PMCID:...PMC5265844Acquired...reactive...perforating...collagenosisA...report...of...a...typical...caseChengwen...Fei,...MD,...Yao...Wang,...MD,...Yu...Gong,...MD,...Hui...Xu,...MD,...Qian...Yu,...MD,...and...Yuling...Shi,...MD,...PhD∗Monitoring...Editor:...Ismael...Maatouk.Department...of...Dermatology,...Shanghai...Tenth...People’s...Hospital,...Tongji...University...School...of...Medicine,...Shanghai,...China.∗Correspondence:...Yuling...Shi,...Department...of...Dermatology,...Shanghai...Tenth...People’s...Hospital,...Tongji...University...School...of...Medicine,...Shanghai...200072,...China...(e-mail:...nc.ude.ijgnot3791gniluyihs).Author...information......Article...notes......Copyright...and...License...information...Received...2016...Jan...12;...Revised...2016...Jun...3;...Accepted...2016...Jun...28.Copyright......2016...the...Author(s)

Clinically,..no..discrimination..between..vasculitic..lesions..and..RPC..lesions..was..made[PubMed]20Gambichler....T,....Birkner....L,....Stcker....M,....et....alEur....J....Dermatol....2000;....11:466–468Role..of..compound..glycyrrhizin..in..clinical..treatmentThis...specimen...demonstrated...all...of...the...typical...signs...of...a...leucocytoclastic...vasculitis...(FigHistopathological...examination...is...crucial...for...differential...diagnosis.We...reviewed...some...cases...of...ARPC...reported...in...the...literature...and...tried...to...summarize...the...clinical...characteristics,...effective...management,...as...well...as...prognosis

J..Dermatol..2010;..37:585–592The..classic..lesion..and..histopathological..examination..are..the..major..distinguishing..characteristicsAbstractBackground:Reactive...perforating...collagenosis...(RPC)...is...a...rare...form...of...transepithelial...elimination,...in...which...altered...collagen...is...extruded...through...the...epidermis2.ConsentThis..patient..signed..informed..consent..for..the..publication..of..this..case..report..and..the..associated..imagesThere..was..no..history..of..oozing..or..vesiculation..during..the..whole..course..of..disease

Some...of...these...lesions...healed...spontaneously...with...atrophic...scars...and...pigmented...maculesSystemic....examination....was....unremarkableIndian...Dermatol...Online...J...2014;...5:236Necrotic....basophilic....collagen....fibers....are....eliminated....to....epidermisAnd....the....blood....glucose....was....controlled....in....a....satisfying....rangeLaboratory...examinations...showed...elevated...blood...glucose...level[PubMed]15Dermatoendocrinology....2009;....1:229–231Cutaneous..examination..revealed..a..palpable..purpura..with..central..necrotic..and..ulcerated..lesions..predominantly..involving..the..lower..extremities..and..petechial..skin..lesions..on..the..trunk..and..forearms c16eaae032
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